Microsoft Defender for Office 365
Also known as MDO
Microsoft's email and collaboration security layer, protecting against phishing, malicious links, and weaponized attachments.
Plan 1 provides Safe Links and Safe Attachments, checking destinations at the moment of click and detonating files before delivery. Plan 2 adds attack simulation training, automated investigation and response, and threat tracking.
Plan 1 is now included in E3 and Business Premium. Plan 2 comes with E5 or the Defender Suite.
Where this comes up
Microsoft Defender for Office 365 sits inside our microsoft 365 and cloud work. If you are trying to work out what this means for your own environment rather than in the abstract, that is the page worth reading next, and a short call will get you a straight answer faster than either.